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Acta Pharmaceutica Sinica ; (12): 1504-1510, 2020.
Article in Chinese | WPRIM | ID: wpr-823297

ABSTRACT

Natural products have been a major source of leading compounds in drug discovery. How to effectively screen active compounds from complex matrix remains an interesting topic. In this review, we comprehensively summarized advanced liquid chromatography based approaches in natural products screening, including pre-column, on-column and post-column screening methods. Their advantages, disadvantages and prospect are also discussed.

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